Target-induced strand release (TISR) from aptamer-DNA duplex: a general strategy for electronic detection of biomolecules ranging from a small molecule to a large protein.

نویسندگان

  • Jyun Yoshizumi
  • Satoshi Kumamoto
  • Mitsunobu Nakamura
  • Kazushige Yamana
چکیده

We describe a general strategy for electronic aptamer-based biosensor that is based on target-induced strand release (TISR) of a redox-modified aptamer from the aptamer-capture DNA duplex bound on an electrode.

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عنوان ژورنال:
  • The Analyst

دوره 133 3  شماره 

صفحات  -

تاریخ انتشار 2008